With the growing cross-country and cross-sector interest in cleanroom technology, the need for a uniform definition of cleanroom standards and norms grew. Due to the far-reaching and complex progress in the development of cleanroom technology across a wide range of areas, there were numerous standards and guidelines before uniform standardization. In our current blog post we outline the historical development of standardization in the field of cleanroom technology and give an insight into the current status quo of the most important guidelines.